flow cytometry analysis of rosa damascena effects on gastric cancer cell line (mkn45)
Authors
abstract
abstract background: gastric cancer is a life threatening disease. recent studies have shown that rosa damascene possesses noticeable biological effects on the human body. this study, investigates the anticancer effect of rosa damascena on gastric cancer cell line mkn45. methods: microscopic studies and mtt assay were used to examine morphological alteration, and cell survival of the cancer cells while exposing to differentvolumes of the essential oilrespectively. in addition, flow cytometry was applied to determine the cell death mechanism of the gastric cancer treated with the essential oil. results: the findings indicate that rosa damascena essential oil affects gastric cancer cells in two distinctive ways: the soluble phase increases cell viability, while the vapor phase decreases cellsurvival. moreover, flow cytometry analysis revealed that apoptosis is the main mechanism accompanied with cell death. conclusion: consequently, rosa damascena essential oil can be used as a potent anticancer agent in the future. however,more evaluation of this essential oil is still needed to elicit its effectivebiological activities.
similar resources
Antioxidant properties of vanadium complexes and their anticancer effects on human gastric cancer cell line MKN45
Introduction: Gastric cancer is the fourth most common cancer worldwide and the second leading cause of death from cancer. In recent years, advances in cancer therapy have raised the specter of developing effective agents of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths in the world. Recently it has been demonstrated that vanadium compounds ex...
full textPharmacological Effects of Rosa Damascena
Rosa damascena mill L., known as Gole Mohammadi in is one of the most important species of Rosaceae family flowers. R. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-HIV, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported for this plant. This article is a comp...
full textEffect of essential oil of Rosa Damascena on human colon cancer cell line SW742
AIM In this study, we report the effect of the essential oil of Rosa Damascena on human colon cancer cell line (SW742) and human fibroblast cells. BACKGROUND Colon cancer is the second most common fatal malignancy. Owing to the existence of many side effects and problems related to common treatments such as surgery, chemotherapy and radiotherapy, alternative treatments are being investigated....
full textAnticancer effect of lactoferrin on Gastric Cancer Cell Line AGS
Background: Lactoferrin is a glycoprotein with a molecular weight of 80 kDa, as a member of the transferring family. In recent investigations the important biological properties such as anti microbial, antiviral and anticancer activity of lactoferrin were studied. In the present study, the effect of antitumor induced by lactoferin was evaluated on stomach cancer cell AGS. Materials and Methods...
full texteffect of essential oil of rosa damascena on human colon cancer cell line sw742
aim: in this study, the effect of the essential oil of rosa damascena on human colon cancer cell line (sw742) and human fibroblast cells has been reported. background : colon cancer is the second lethal disease after lung cancer. owing to the existence of many side effects and problems related to common treatments such as surgery, chemotherapy and radiotherapy, better substitution is highly nee...
full textAnticancer effects of Perovskia abrotanoides hydroalcoholic extracts on MKN45 gastric cancer cells
Introduction: Gastric cancer is the fourth most common cancer worldwide and the second leading cause of death from cancer. Given that existing treatments for it, but the high cost and side effects, have not demonstrated full efficacy and rely on traditional medicine and medicinal plants due to the antioxidant activity of Provskia abrotanoides, this study was performed to investigate the effects...
full textMy Resources
Save resource for easier access later
Journal title:
iranian journal of cancer preventionجلد ۶، شماره ۰۳، صفحات ۳۰-۶
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023